Publications » Institute of Reconstructive Neurobiology

Publications

2020

Paß, T., Aßfalg, M., Tolve, M., Blaess, S., Rothermel, M., Wiesner, R.J., Ricke, K.M. (2020)
The impact of mitochondrial dysfunction on dopaminergic neurons in the olfactory bulb and odor detection
Mol Neurobiol. 57:3646-3657. doi: 10.1007/s12035-020-01947-w.

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2019

van Loo, K.M.J., Rummel, C.K., Pitsch, J., Müller, A. J., Bikbaev, A.F., Martinez Chavez, E., Blaess, S., Dietrich, D., Heine, M., Becker, A.J., Schoch, S. (2019)
Calcium channel subunit α2δ4 is regulated by early growth response 1 and facilitates epileptogenesis
J Neurosci. pii: 1731-18. doi: 10.1523/JNEUROSCI.1731-18.2019

Vaswani, A.R.Weykopf, B., Hagemann, C., Fried, H.-U., Brüstle, O., Blaess, S. (2019)
Correct setup of the substantia nigra requires Reelin-mediated fast, laterally-directed migration of dopaminergic neurons
eLife. 8:e41623. doi: 10.7554/eLife.41623

Weykopf, B. , Haupt, S. , Jungverdorben, J. , Flitsch, L. J., Hebisch, M. , Liu, G. , Suzuki, K. , Belmonte, J. C., Peitz, M. , Blaess, S. , Till, A., Brüstle, O. (2019)
Induced pluripotent stem cell‐based modeling of mutant LRRK2‐associated Parkinson's Disease
Eur J Neurosci. 49:561-589. doi:10.1111/ejn.14345

Brodski, C., Blaess, S., Partanen, J., Prakash, N. (2019)
Crosstalk of intercellular signaling pathways in the generation of midbrain dopaminergic neurons in vivo and from stem cells
J Dev Biol. 7:3. doi: 10.3390/jdb7010003. Review

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2018

Martinez-Chavez, E., Scheerer, C., Wizenmann, A., Blaess, S. (2018)
The zinc finger transcription factor Gli3 is a regulator of precerebellar neuronal migration
Development. 145:dev166033. doi: 10.1242/dev.166033

Jovanovic, V.M., Salti, A., Tilleman, H., Zega, K., Jukic, M.M., Zou, H., Friedel, R.H., Prakash, N., Blaess, S., Edenhofer, F., Brodski, C. (2018)
BMP/SMAD pathway promotes neurogenesis of midbrain dopaminergic neurons in vivo and in human induced pluripotent and neural stem cells
J Neurosci. 38:1662-1676. doi: 10.1523/JNEUROSCI.1540-17.2018

Münst, S., Koch, P., Kesavan, J., Alexander-Mays, M., Münst, B., Blaess, S., Brüstle, O. (2018)
In vitro segregation and isolation of human pluripotent stem cell-derived neural crest cells
Methods. 133:65-80. doi: 10.1016/j.ymeth.2017.09.012

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2017

Sciandra, F., Scicchitano, B.M., Signorino, G., Bigotti, M.G., Tavazzi, B., Lombardi, F., Bozzi, M., Sica, G., Giardina, B., Blaess, S., Brancaccio, A. (2017)
Evaluation of the effect of a floxed Neo cassette within the dystroglycan (Dag1) gene
BMC Res Notes. 10:601. doi: 10.1186/s13104-017-2926-9

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2016

Gazea, M., Tasouri, E., Tolve, M., Bosch, V., Kabanova, A., Gojak, C., Kurtulmus, B., Novikov, O., Spatz, J., Pereira, G., Hübner, W., Brodski, C., Tucker, K.L., Blaess, S. (2016)
Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain
Dev Biol. 2016 Jan 1;409(1):55-71. doi: 10.1016/j.ydbio.2015.10.033.

Gazea, M.*, Tasouri, E.*, Heigl, T., Bosch, V., Tucker, K.L., Blaess, S. (2016)
Definition of a critical spatiotemporal window within which primary cilia control midbrain dopaminergic neurogenesis
Neurogenesis (Austin). 2016 Oct 20;3(1):e1248206. doi: 10.1080/23262133.2016.1248206.
*Authors contributed equally

Vaswani, A.R., Blaess S. (2016)
Reelin signaling in the migration of ventral brain stem and spinal cord neurons
Front Cell Neurosci. 2016 Mar 11;10:62. doi: 10.3389/fncel.2016.00062. eCollection 2016. Review.

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2015

Kabanova, A*., Pabst, M., Lorkowski*, M., Braganza, O., Boehlen, A., Nikbakht, N., Pothmann, L., Vaswani, A.R., Musgrove, R., Di Monte, D.A., Sauvage, M., Beck, H., Blaess, S. (2015)
Function and developmental origin of a mesocortical inhibitory circuit
Nat Neurosci. 2015 Jun;18(6):872-82. doi: 10.1038/nn.4020.
*Authors contributed equally

Blaess, S., Szabó, N., Haddad-Tóvolli, N., Zhou, X., Álvarez-Bolado, G. (2015)
Sonic hedgehog signalling in the development of the mouse hypothalamus
Front Neuroanat 2015 Jan 6;8:156. doi: 10.3389/fnana.2014.00156. eCollection 2014. Review.

Blaess, S., Ang, S.-L. (2015)
Genetic control of midbrain dopaminergic neuron development
Wiley Interdiscip Rev Dev Biol. 2015 Mar-Apr;4(2):113-34. doi: 10.1002/wdev.169.

Haddad-Tóvolli, R., Paul, F.A., Zhang, Y., Zhou, X., Theil, T., Puelles, L., Blaess, S., Alvarez-Bolado, G. (2015)
Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus
Front Neuroanat 2015 Mar 25;9:34. doi: 10.3389/fnana.2015.00034. eCollection 2015.

Bodea, G.O., Blaess, S. (2015)
Establishing diversity in the dopaminergic system
FEBS Lett. 589(24):3773–3785. doi: 10.1016/j.febslet.2015.09.016. Review.

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2014

Karus, M., Blaess, S., Brüstle, O. (2014)
Self-organisation of neural tissue architectures from pluripotent stem cells
J Comp Neurol 522(12):2831-2844. doi: 10.1002/cne.23608.

Bodea, G.O., Spille, J.H., Abe, P., Andersson, A.S., Acker-Palmer, A., Stumm, R., Kubitscheck, U., Blaess S. (2014)
Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.
Development 141(3):661-73. doi: 10.1242/dev.099937.

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2013

Haseleu, J., Anlauf, E., Blaess, S., Endl, E., Derouiche, A. (2013)
Studying subcellular detail in fixed astrocytes: dissociation of morphologically intact glial cells (DIMIGs)
Front Cell Neurosci 7:54 doi: 10.3389/fncel.2013.00054.

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2012

Haddad-Tóvolli, R., Heide, M., Zhou, X., Blaess, S., Alvarez-Bolado, G. (2012)
Mouse thalamic differentiation: Gli-dependent pattern and Gli-independent prepattern.
Front Neurosci 6:27

Bodea, G.O., Blaess, S. (2012)
Organotypic slice cultures of embryonic ventral midbrain: a system to study dopaminergic neuronal development in vitro
J Vis Exp 31;(59) doi: 10.3791/3350

Alvarez-Bolado, G., Paul, F.A., Blaess, S. (2012)
Sonic hedgehog lineage in the mouse hypothalamus: From progenitor domains to hypothalamic regions
Neural Dev 20;7(1):4

Derouiche, A., Pannicke, T., Haseleu, J., Blaess, S., Grosche, J., Reichenbach, A. (2012)
Beyond polarity: functional membrane domains in astrocytes and Müller cells.
Neurochem Res. 37(11):2513-23

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2011

Blaess, S., Bodea, G.O., Kabanova, A., Chanet, S., Mugniery, E., Derouiche, A., Stephen, D., Joyner, A.L. (2011)
Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei
Neural Dev 20:6(1):29

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2009

Hammond, R.*, Blaess, S.*, Abeliovich, A. (2009)
Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons
PLoS ONE. 2009 4(9): e7007
*Authors contributed equally

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2008

Blaess, S., Stephen, D., Joyner, A.L. (2008)
Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling
Development 135(12):2093-2103

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2006

Corrales, J.D., Blaess, S., Mahoney, E.M., Joyner, A.L. (2006)
The level of Sonic hedgehog signaling regulates the complexity of cerebellar foliation
Development 133(9):1811-1821

Blaess, S., Corrales, J.D., Joyner, A.L. (2006)
Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region
Development 133(9):1799-1809

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2005

Zervas, M., Blaess, S., Joyner, A.L. (2005)
Classical embryological studies and modern genetic analysis of midbrain and cerebellum development
Current Topics in Developmental Biology 69:101-138

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2004

Corrales, J.D., Rocco, G.L., Blaess, S., Guo, Q., Joyner, A.L. (2004)
Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development
Development 131(22):5581-5590

White, D.E., Kurpios, N.A., Zuo, D., Hassell, J.A., Blaess, S., Mueller, U., Muller, W.J. (2004)
Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
Cancer Cell 6(2):159-170

Blaess, S.*, Graus-Porta, D.*, Belvindrah, R., Radakovits, R., Pons, S., Littlewood-Evans, A., Senften, M., Guo, H., Li, Y., Miner, J.H., Reichardt, L.F., Müller, U. (2004)
β1-integrins are critical for cerebellar granule cell precursor proliferation
J Neurosci 24(13):3402-3412
* Authors contributed equally

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2001

Graus-Porta, D.*, Blaess, S.*, Senften, M., Littlewood-Evans, A., Damsky, C., Huang, Z., Orban, P., Klein, R., Schittny, J.C., Müller, U. (2001)
β1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex
Neuron 16;31(3):367-379
*Authors contributed equally

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1998

Blaess, S., Kammerer, R.A., Hall. H. (1998)
Structural analysis of the sixth immunoglobulin-like domain of mouse neural cell adhesion molecule L1 and its interactions with αvβ3, αIIbβ3, and α5β1 integrins
J Neurochem 71(6):2615-2625

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Institute of Reconstructive Neurobiology

University of Bonn
LIFE & BRAIN Center
Venusberg-Campus 1
Building 76
D-53105 Bonn/Germany

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Phone +49 (0)228 - 6885 - 500
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