Institute of Reconstructive Neurobiology
Director: Oliver Brüstle
Due to the limited regenerative potential of the central nervous system, brain and spinal cord repair represent some of the biggest challenges in contemporary biomedicine. The availability of self-renewing stem cells has provided new perspectives for the development of neuroregenerative therapies. A key focus of our research is the derivation of defined neurons and glia from pluripotent embryonic stem cells (ES cells). Using a variety of transplantation and disease models, we explore the potential of these cells to integrate into the nervous system and to contribute to functional repair.