2011

1. Ablasser, A., and Hornung, V. (2011). Where, in antiviral defense, does IFIT1 fit? Nat Immunol. 12, 588-590.

2. Agaoglu, F.Y., Kovancilar, M., Dizdar, Y., Darendeliler, E., Holdenrieder, S., Dalay, N., and Gezer, U. (2011). Investigation of miR-21, miR-141, and miR-221 in blood circulation of patients with prostate cancer. Tumour Biol. 32, 583-588.

3. Amigo, L., Husche, C., Zanlungo, S., Lütjohann, D., Arrese, M., Miquel, J.F., Rigotti, A., and Nervi, F. (2011). Cholecystectomy increases hepatic triglyceride content and very-low-density lipoproteins production in mice. Liver Int. 31, 52-64.

4. Bartels, E., Draaken, M., Kazmierczak, B., Spranger, S., Schramm, C., Baudisch, F., Nöthen, M.M., Schmiedeke, E., Ludwig, M., and Reutter, H. (2011). De novo Partial Trisomy 18p and Partial Monosomy 18q in a Patient with Anorectal Malformation. Cytogenet Genome Res. 134, 243-248.

5. Bauer, J., Bös, M., Rück, J., and Stoffel-Wagner, B. (2011a). [Evaluation of folate substitution in women with epilepsy. Determination of erythrocyte folic acid concentrations]. Nervenarzt. 82, 459-461.

6. Bauer, J., Dierkes, H., Burr, W., Reuber, M., and Stoffel-Wagner, B. (2011b). Disease- and treatment-related effects on the pituitary-gonadal functional axis: a study in men with epilepsy. J Neurol. 258, 1080-1084.

7. Bauernfeind, F., Ablasser, A., Bartok, E., Kim, S., Schmid-Burgk, J., Cavlar, T., and Hornung, V. (2011a). Inflammasomes: current understanding and open questions. Cell Mol Life Sci. 68, 765-783.

8. Bauernfeind, F., Bartok, E., Rieger, A., Franchi, L., NË™Òez, G., and Hornung, V. (2011b). Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J Immunol. 187, 613-617.

9. Berbee, J.F.P., Vanmierlo, T., Abildayeva, K., Blokland, A., Jansen, P.J., Lütjohann, D., Gautier, T., Sijbrands, E., Prickaerts, J., Hadfoune, M., et al. (2011). Apolipoprotein CI knock-out mice display impaired memory functions. J Alzheimers Dis. 23, 737-747.

10. Blufpand, H.N., Tromp, J., Abbink, F.C., Stoffel-Wagner, B., Bouman, A.A., Schouten-van Meeteren, A.Y., van Wijk, J.A., Kaspers, G.J., and Bökenkamp, A. (2011). Cystatin C more accurately detects mildly impaired renal function than creatinine in children receiving treatment for malignancy. Pediatr Blood Cancer. 57, 262-267.

11. Bökenkamp, A., and Ludwig, M. (2011). Disorders of the renal proximal tubule. Nephron Physiol. 118, p1-6.

12. Debald, M., Franken, S., Heukamp, L.C., Linke, A., Wolfgarten, M., Braun, M., Walgenbach, K.J., Rudlowski, C., Holdenrieder, S., Kuhn, W., et al. (2011a). CALPONIN-H2 AS POTENTIAL SERUM-BASED MARKER FOR EARLY BREAST CANCER DETECTION. Anticancer Res. 31, 1966-1966.

13. Debald, M., Franken, S., Heukamp, L.C., Linke, A., Wolfgarten, M., Walgenbach, K.J., Braun, M., Rudlowski, C., Gieselmann, V., Kuhn, W., et al. (2011b). Identification of specific nuclear structural protein alterations in human breast cancer. J Cell Biochem. 112, 3176-3184.

14. Dombrowski, Y., Peric, M., Koglin, S., Kammerbauer, C., Göfl, C., Anz, D., Simanski, M., Gläser, R., Harder, J., Hornung, V., et al. (2011). Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions. Sci Transl Med. 3, 82ra38.

15. Draaken, M., Giesen, C.A., Kesselheim, A.L., Jabs, R., Aretz, S., Kugaudo, M., Chrzanowska, K.H., Krajewska-Walasek, M., and Ludwig, M. (2011). Maternal de novo triple mosaicism for two single OCRL nucleotide substitutions (c.1736A>T, c.1736A>G) in a Lowe syndrome family. Hum Genet. 129, 513-519.

16. Ebert, G., Poeck, H., Lucifora, J., Baschuk, N., Esser, K., Esposito, I., Hartmann, G., and Protzer, U. (2011). 5' Triphosphorylated small interfering RNAs control replication of hepatitis B virus and induce an interferon response in human liver cells and mice. Gastroenterology. 141, 696-706, 706.e691.

17. El-Maarri, O., Walier, M., Behne, F., van ‹üm, J., Singer, H., Diaz-Lacava, A., Nüsgen, N., Niemann, B., Watzka, M., Reinsberg, J., et al. (2011). Methylation at Global LINE-1 Repeats in Human Blood Are Affected by Gender but Not by Age or Natural Hormone Cycles. PLoS ONE. 6, e16252.

18. Finger, R.P., Coch, C., Coenen, M., Mengel, M., Hartmann, G., and Holz, F.G. (2011). [Basic principles, planning and implementation of non-commercial clinical trials]. Ophthalmologe. 108, 25-32.

19. Fleischhacker, M., Schmidt, B., Weickmann, S., Fersching, D.M., Leszinski, G.S., Siegele, B., Stötzer, O.J., Nagel, D., and Holdenrieder, S. (2011). Methods for isolation of cell-free plasma DNA strongly affect DNA yield. Clin Chim Acta. 412, 2085-2088.

20. Geiser, F., Conrad, R., Imbierowicz, K., Meier, C., Liedtke, R., Klingmüller, D., Oldenburg, J., and Harbrecht, U. (2011). Coagulation activation and fibrinolysis impairment are reduced in patients with anxiety and depression when medicated with serotonergic antidepressants. Psychiatry Clin Neurosci. 65, 518-525.

21. Gerhardt, T., Poge, U., Stoffel-Wagner, B., Palmedo, H., Sauerbruch, T., and Woitas, R.P. (2011a). Is beta-trace protein an alternative marker of glomerular filtration rate in liver transplant recipients? Liver Int. 31, 1345-1351.

22. Gerhardt, T., Pöge, U., Stoffel-Wagner, B., Palmedo, H., Sauerbruch, T., and Woitas, R.P. (2011b). Creatinine-based glomerular filtration rate estimation in patients with liver disease: the new Chronic Kidney Disease Epidemiology Collaboration equation is not better. Eur J Gastroenterol Hepatol. 23, 969-973.

23. Glockner, F., Meske, V., Lutjohann, D., and Ohm, T.G. (2011). Dietary Cholesterol and Its Effect on Tau Protein: A Study in Apolipoprotein E-Deficient and P301L Human Tau Mice. J Neuropathol Exp Neurol. 70, 292-301.

24. Grimaldi, K.A., Look, M.P., Scioli, G.A., Clavero, J.C., Marinos, S., and Tagaris, T. (2011). Personal genetics: regulatory framework in Europe from a service provider's perspective. Eur J Hum Genet. 19, 382-388.

25. Herberhold, S., Coch, C., Zillinger, T., Hommertgen, B., Busch, N., Schuberth, C., Hartmann, E., Wimmenauer, V., Hagmann, C.A., Lüdenbach, B., et al. (2011). Delivery with polycations extends the immunostimulant Ribomunyl(Æ) into a potent antiviral Toll-like receptor 7/8 agonist. Antivir Ther. 16, 751-758.

26. Hoyer, F.F., Steinmetz, M., Zimmer, S., Becker, A., Lütjohann, D., Buchalla, R., Zimmer, A., and Nickenig, G. (2011). Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo. J Mol Cell Cardiol. 51, 1007-1014.

27. Husche, C., Weingärtner, O., Pettersson, H., Vanmierlo, T., Böhm, M., Laufs, U., and Lütjohann, D. (2011). Validation of an isotope dilution gas chromatography-mass spectrometry method for analysis of 7-oxygenated campesterol and sitosterol in human serum. Chem Phys Lipids. 164, 425-431.

28. Jacobs, C., Duewell, P., Heckelsmiller, K., Wei, J.W., Bauernfeind, F., Ellermeier, J., Kisser, U., Bauer, C.A., Dauer, M., Eigler, A., et al. (2011). An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma. Int J Cancer. 128, 897-907.

29. Kaut, O., Allert, N., Coch, C., Paus, S., Grzeska, A., Minnerop, M., and Wüllner, U. (2011). Stochastic resonance therapy in Parkinson's disease. NeuroRehabilitation. 28, 353-358.

30. Klingmüller, D., and AllÈra, A. (2011). [Endocrine disruptors: hormone-active chemicals from the environment: a risk to humans?]. Dtsch Med Wochenschr. 136, 967-972.

31. Koerner, P., Traeger, T., Mehmcke, H., Cziupka, K., Kessler, W., Busemann, A., Diedrich, S., Hartmann, G., Heidecke, C.D., and Maier, S. (2011). Stimulation of TLR7 prior to polymicrobial sepsis improves the immune control of the inflammatory response in adult mice. Inflamm Res. 60, 271-279.

32. Kohles, N., Nagel, D., Jüngst, D., Durner, J., Stieber, P., and Holdenrieder, S. (2011). Relevance of circulating nucleosomes and oncological biomarkers for predicting response to transarterial chemoembolization therapy in liver cancer patients. BMC Cancer. 11, 202.

33. Kristof, R.A., Grote, A., Redel, L., Neuloh, G., Klingmüller, D., and Schramm, J. (2011). The common consensus criteria have high predictive values for long-term postoperative acromegaly remission. Acta Neurochir (Wien). 153, 19-25.

34. Kukolja, J., Klingmüller, D., Maier, W., Fink, G.R., and Hurlemann, R. (2011). Noradrenergic-glucocorticoid modulation of emotional memory encoding in the human hippocampus. Psychol Med. 41, 2167-2176.

35. Kübler, K., tho Pesch, C., Gehrke, N., Riemann, S., Dassler, J., Coch, C., Landsberg, J., Wimmenauer, V., Pölcher, M., Rudlowski, C., et al. (2011). Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells. Eur J Immunol. 41, 3028-3039.

36. Linnebank, M., Moskau, S., Semmler, A., Widman, G., Stoffel-Wagner, B., Weller, M., and Elger, C.E. (2011a). Antiepileptic drugs interact with folate and vitamin B12 serum levels. Ann Neurol. 69, 352-359.

37. Linnebank, M., Moskau, S., Semmler, A., Widman, G., Stoffel-Wagner, B., Weller, M., and Elger, C.E. (2011b). Vitamin B12, Folate and Hyperhomocysteinemia in Patients with Epilepsy Reply. Ann Neurol. 69, 1068-1068.

38. Lippmann, J., Müller, H., Naujoks, J., Tabeling, C., Shin, S., Witzenrath, M., Hellwig, K., Kirschning, C.J., Taylor, G.A., Barchet, W., et al. (2011). Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell Microbiol. 13, 1668-1682.

39. Ludwig, M., and Sethi, S.K. (2011). Novel techniques and newer markers for the evaluation of "proximal tubular dysfunction". Int Urol Nephrol. 43, 1107-1115.

40. Mühleisen, T.W., Basmanav, F.B., Forstner, A.J., Mattheisen, M., Priebe, L., Herms, S., Breuer, R., Moebus, S., Nenadic, I., Sauer, H., et al. (2011). Resequencing and follow-up of neurexin 1 (NRXN1) in schizophrenia patients. Schizophr Res. 127, 35-40.

41. Ostrowska, M., Banaszkiewicz, K., Ki?awiec, A., RÛg, T., Lütjohann, D., and Szczudlik, A. (2011). Cerebrotendinous xanthomatosis: a rare cause of spinocerebellar syndrome. Neurol Neurochir Pol. 45, 600-603.

42. Oswald, S., Nassif, A., Modess, C., Keiser, M., Ulrich, A., Runge, D., Hanke, U., Lutjohann, D., Engel, A., Weitschies, W., and Siegmund, W. (2011). Drug Interactions Between the Immunosuppressant Tacrolimus and the Cholesterol Absorption Inhibitor Ezetimibe in Healthy Volunteers. Clin Pharmacol Ther. 89, 524-528.

43. Peters, J., Block, W., Oswald, S., Freyer, J., Grube, M., Kroemer, H.K., Lammer, M., Luetjohann, D., Venner, M., and Siegmund, W. (2011). Oral absorption of clarithromycin is nearly abolished by chronic comedication of rifampicin in foals. Drug Metab Dispos. 39, 1643-1649.

44. Pöge, U., Gerhardt, T., Stoffel-Wagner, B., Sauerbruch, T., and Woitas, R.P. (2011). Validation of the CKD-EPI formula in patients after renal transplantation. Nephrol Dial Transplant. 26, 4104-4108.

45. Qi, L., Chen, K., Hur, D.J., Yagnik, G., Lakshmanan, Y., Kotch, L.E., Ashrafi, G.H., Martinez-Murillo, F., Kowalski, J., Naydenov, C., et al. (2011). Genome-wide expression profiling of urinary bladder implicates desmosomal and cytoskeletal dysregulation in the bladder exstrophy-epispadias complex. Int J Mol Med. 27, 755-765.

46. Refke, M., Pasternack, S.M., Fiebig, B., Wenzel, S., Ishorst, N., Ludwig, M., Nöthen, M.M., Seyger, M.M., Hamel, B.C., and Betz, R.C. (2011). Functional analysis of splice site mutations in the human hairless (HR) gene using a minigene assay. Br J Dermatol. 165, 1127-1132.

47. Reutter, H., Boyadjiev, S.A., Gambhir, L., Ebert, A.K., Rösch, W.H., Stein, R., Schröder, A., Boemers, T.M., Bartels, E., Vogt, H., et al. (2011). Phenotype severity in the bladder exstrophy-epispadias complex: analysis of genetic and nongenetic contributing factors in 441 families from north america and europe. J Pediatr. 159, 825-831.e821.

48. Schlaweck, S., Zimmer, S., Struck, R., Bartok, E., Werner, N., Bauernfeind, F., Latz, E., Nickenig, G., Hornung, V., and Ghanem, A. (2011). Critical role of nucleotide-binding oligomerization domain-like receptor 3 in vascular repair. Biochem Biophys Res Commun. 411, 627-631.

49. Schramm, C., Draaken, M., Bartels, E., Boemers, T.M., Aretz, S., Brockschmidt, F.F., Nöthen, M.M., Ludwig, M., and Reutter, H. (2011a). De novo microduplication at 22q11.21 in a patient with VACTERL association. Eur J Med Genet. 54, 9-13.

50. Schramm, C., Draaken, M., Bartels, E., Boemers, T.M., Schmiedeke, E., Grasshoff-Derr, S., Märzheuser, S., Hosie, S., Holland-Cunz, S., Baudisch, F., et al. (2011b). De novo duplication of 18p11.21-18q12.1 in a female with anorectal malformation. Am J Med Genet A. 155A, 445-449.

51. Schramm, C., Draaken, M., Tewes, G., Bartels, E., Schmiedeke, E., Märzheuser, S., Grasshoff-Derr, S., Hosie, S., Holland-Cunz, S., Priebe, L., et al. (2011c). Autosomal-dominant non-syndromic anal atresia: sequencing of candidate genes, array-based molecular karyotyping, and review of the literature. Eur J Pediatr. 170, 741-746.

52. Tasic, V., Lozanovski, V.J., Korneti, P., Ristoska-Bojkovska, N., Sabolic-Avramovska, V., Gucev, Z., and Ludwig, M. (2011). Clinical and laboratory features of Macedonian children with OCRL mutations. Pediatr Nephrol. 26, 557-562.

53. van den Boorn, J.G., Schlee, M., Coch, C., and Hartmann, G. (2011). SiRNA delivery with exosome nanoparticles. Nat Biotechnol. 29, 325-326.

54. Vanmierlo, T., Popp, J., Kölsch, H., Friedrichs, S., Jessen, F., Stoffel-Wagner, B., Bertsch, T., Hartmann, T., Maier, W., von Bergmann, K., et al. (2011a). The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease. Acta Psychiatr Scand. 124, 184-192.

55. Vanmierlo, T., Rutten, K., Dederen, J., Bloks, V.W., van Vark-van der Zee, L.C., Kuipers, F., Kiliaan, A., Blokland, A., Sijbrands, E.J., Steinbusch, H., et al. (2011b). Liver X receptor activation restores memory in aged AD mice without reducing amyloid. Neurobiol Aging. 32, 1262-1272.

56. Vanmierlo, T., Rutten, K., van Vark-van der Zee, L.C., Friedrichs, S., Bloks, V.W., Blokland, A., Ramaekers, F.C., Sijbrands, E., Steinbusch, H., Prickaerts, J., et al. (2011c). Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice. Plant Foods Hum Nutr. 66, 149-156.

57. Vrljicak, K., Batini, D., Milosevi, D., Nizi?-Stancin, L., and Ludwig, M. (2011). A boy with Dent-2 disease. Coll Antropol. 35, 925-928.

58. Weber, S., Thiele, H., Mir, S., Toliat, M.R., Sozeri, B., Reutter, H., Draaken, M., Ludwig, M., Altmüller, J., Frommolt, P., et al. (2011). Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome. Am J Hum Genet. 89, 668-674.

59. Weingärtner, O., Lütjohann, D., Böhm, M., and Laufs, U. (2011a). [Cholesterol homeostasis and cardiovascular risk]. Dtsch Med Wochenschr. 136, 34-38.

60. Weingärtner, O., Lütjohann, D., Vanmierlo, T., Müller, S., Günther, L., Herrmann, W., Böhm, M., Laufs, U., and Herrmann, M. (2011b). Markers of enhanced cholesterol absorption are a strong predictor for cardiovascular diseases in patients without diabetes mellitus. Chem Phys Lipids. 164, 451-456.

61. Weingärtner, O., Ulrich, C., Lütjohann, D., Ismail, K., Schirmer, S.H., Vanmierlo, T., Böhm, M., and Laufs, U. (2011c). Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice. Cardiovasc Res. 90, 484-492.

62. Winter, M., Beer, H.D., Hornung, V., Krämer, U., Schins, R.P., and Förster, I. (2011). Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells. Nanotoxicology. 5, 326-340.

63. Wulfken, L.M., Moritz, R., Ohlmann, C., Holdenrieder, S., Jung, V., Becker, F., Herrmann, E., Walgenbach-Brünagel, G., von Ruecker, A., Müller, S.C., and Ellinger, J. (2011). MicroRNAs in renal cell carcinoma: diagnostic implications of serum miR-1233 levels. PLoS ONE. 6, e25787.

64. Zahn, S., Barchet, W., Rehkämper, C., Hornung, T., Bieber, T., Tüting, T., and Wenzel, J. (2011). Enhanced skin expression of melanoma differentiation-associated gene 5 (MDA5) in dermatomyositis and related autoimmune diseases. J Am Acad Dermatol. 64, 988-989.

65. Zimmer, S., Steinmetz, M., Asdonk, T., Motz, I., Coch, C., Hartmann, E., Barchet, W., Wassmann, S., Hartmann, G., and Nickenig, G. (2011). Activation of endothelial toll-like receptor 3 impairs endothelial function. Circ Res. 108, 1358-1366.

66. Zur, B., Hildesheim, A., Ludwig, M., and Stoffel-Wagner, B. (2011a). A first report on Hb Q-Iran in association with alpha-thalassemia in a case of spinal ischemia. Clin Lab. 57, 221-224.

67. Zur, B., Look, M., Holdenrieder, S., and Stoffel-Wagner, B. (2011b). Elevated plasma myeloperoxidase concentration in adults with obesity. Clin Chim Acta. 412, 1891-1892.

68. Zur, B., Ludwig, M., and Stoffel-Wagner, B. (2011c). Hemoglobin Hasharon and Hemoglobin NYU in subjects of German origin. Biochem Medica. 21, 321-325.

69. Züst, R., Cervantes-Barragan, L., Habjan, M., Maier, R., Neuman, B.W., Ziebuhr, J., Szretter, K.J., Baker, S.C., Barchet, W., Diamond, M.S., et al. (2011). Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol. 12, 137-143.