Supportive Care in Cancer 6(3): 233-236, 1998.
Spitzer TR, Grunberg SM, Dicato MA
The treatment of nausea and vomiting in patients receiving high doses of irradiation and/or chemotherapeutic agents as preparation for hematopoietic stem cell transplantation is discussed. Such patients have very high rates of both early and delayed emesis. Based on the available evidence it is recommended that 5-HT3 receptor antagonists be used to combat emesis in this setting. Continued research is also required to define the optimal antiemetic strategy for these patients.
Rheinische Friedrich- Wilhelms- Universität Bonn