Medline: 6718798

Revue D'Epidemiologie et de Sante Publique 32(1): 57-61, 1984.

Investigating the adenocarcinoma of unknown origin (ACUP): a cost benefit analysis.

Maisey MN, Ellam SV


This paper attempts to assess three approaches to the investigation of a patient with histological metastatic adenocarcinoma when the primary tumour of origin is not clear on the initial presentation. These different approaches are evaluated semi-quantitatively. Estimated costs and morbidity of investigations and treatment, increased survival, and improvement in quality of life are taken into account in this analysis. A sample schema of investigation which will maximise the potential benefit as well as minimise the cost to the health service resources and the human cost to the patient is proposed.

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