Medline: 6869596

American Journal of Psychiatry 140(8): 1074-1076, 1983.

Tricyclic antidepressants for children with cancer.

Pfefferbaum-Levine B, Kumor K, Cangir A, et al.


Eight depressed children with cancer had a rapid clinical response to low doses of imipramine or amitriptyline. Because of the many variables affecting cancer patients, the mechanism by which tricyclic antidepressant treatment produced this response is unclear.

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