Medline: 10950375

Seminars in Oncology 27(4): 480-488, 2000.

Human immunodeficiency virus-associated Hodgkin's disease.

Spina M, Vaccher E, Nasti G, et al.


Hodgkin's disease represents the most common type of non-acquired immunodeficiency virus (AIDS)-defining tumor that occurs in the human immunodeficiency virus (HIV)-positive population. More than 300 cases of Hodgkin's disease in HIV-infected individuals have been reported, mainly from the European countries (ie, Italy, Spain, and France) and to a lesser extent from the United States. All series have documented unusually aggressive tumor behavior, including a higher frequency of unfavorable histologic subtypes, advanced stages, and poorer therapeutic outcome, as compared with the behavior of Hodgkin's disease outside of the HIV setting.

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Dr. G. Quade