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Constipation, impaction, and bowel obstruction

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Introduction
Overview
Constipation
Impaction
Bowel Obstruction
To Learn More
About PDQ


CancerMail from the National Cancer Institute


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Information from PDQ for Patients


INTRODUCTION

This patient summary on constipation, impaction, and bowel obstruction is adapted from a summary written for health professionals by cancer experts. This and other credible information about cancer treatment, screening, prevention, supportive care, and ongoing clinical trials, is available from the National Cancer Institute. Constipation, impaction, and bowel obstruction are common problems for cancer patients, with causes that include the cancer itself or treatment of the cancer. This brief summary describes the differences between constipation, impaction, and bowel obstruction, their causes and treatment. Treatment of children is different from adults. The doctor will prescribe treatments according to the child's age and diagnosis.


OVERVIEW

Constipation, impaction, and bowel obstruction are common problems for cancer patients. The growth and spread of cancer, and cancer treatment, contributes to these conditions.

Constipation is the slow movement of feces (stool or body wastes) through the large intestine resulting in infrequent bowel movements and the passage of dry, hard stools. The longer it takes for the stool to move through the large intestine, the more fluid is absorbed and the drier and harder the stool becomes.

Constipation is annoying and uncomfortable, but fecal impaction (a collection of dry, hard stool in the colon or rectum) can be life-threatening. Patients with a fecal impaction may not have gastrointestinal symptoms. Instead they may have circulation, heart, or breathing problems. If fecal impaction is not recognized, the signs and symptoms will get worse and the patient could die.

A bowel obstruction is a partial or complete blockage of the small or large intestine by a process other than fecal impaction. Bowel obstructions are classified by the type of obstruction, how the obstruction occurred, and where it is. Tumors growing inside or outside the bowel, and scar tissue that develops after surgery, can affect bowel function and cause a partial or complete obstruction. Patients who have colostomies are especially at risk of developing constipation, which can lead to bowel obstruction.

Inactivity, immobility, or physical and social barriers (for example, bathrooms being unavailable or inconveniently located) can make constipation worse. Depression and anxiety caused by cancer treatment or cancer pain can also lead to constipation. The most common causes of constipation are not drinking enough fluids and taking pain medications.


CONSTIPATION

Description and Causes

Common factors that may cause constipation in healthy people are eating a low-fiber diet, postponing visits to the toilet, using laxatives and enemas excessively, not drinking enough fluids, and exercising too little. In persons with cancer, constipation may be a symptom of cancer, a result of a growing tumor, or a result of cancer treatment. Constipation may also be a side effect of medications for cancer or cancer pain and may be a result of other changes in the body (organ failure, decreased ability to move, and depression). Other causes of constipation include dehydration and not eating enough. Cancer, cancer treatment, aging, and declining health can contribute to causing constipation.

More specific causes of constipation and bowel impaction include:

Diet

Changed Bowel Habits
Immobility and Lack of Exercise
Medications
Bowel Disorders
Muscle and Nerve Disorders (nerve damage can lead to loss of muscle tone in the bowel) Body Metabolism Disorders
Environmental Factors

Assessment of Constipation

A medical history and physical examination can identify the causes of constipation. The examination may include a digital rectal exam (the doctor inserts a gloved, lubricated finger into the rectum to check for stool impaction) or a test for blood in the stool. If cancer is suspected, a thorough examination of the rectum and colon may be done with a lighted tube inserted through the anus and into the colon. The following questions may be asked:

Treatment

Treatment of constipation includes prevention (if possible), elimination of possible causes, and limited-use of laxatives. Suggestions for the patient's treatment plan may include the following:


IMPACTION

Description and Causes

Five major factors can cause impaction: opioid pain medications, inactivity over a long period, changes in diet, mental illness, and long-term use of laxatives. Regular use of laxatives for constipation contributes most to the development of constipation and impaction. Repeated use of laxatives in higher and higher doses make the colon less able to signal the need to have a bowel movement.

Patients with impaction may have symptoms similar to patients with constipation, or they may have back pain (the impaction presses on sacral nerves) or bladder problems (the impaction presses on the ureters, bladder, or urethra). The patient's abdomen may become enlarged causing difficulty breathing, rapid heartbeat, dizziness, and low blood pressure. Other symptoms can include explosive diarrhea (as stool moves around the impaction), leaking stool when coughing, nausea, vomiting, abdominal pain, and dehydration. Patients who have an impaction may become very confused and disoriented with rapid heartbeat, sweating, fever, and high or low blood pressure.

Assessment of Impaction

The doctor will ask questions similar to those in the "Assessment of Constipation" section and do a physical examination to find out if the patient has an impaction. The examination may also include x-rays of the abdomen and/or chest, blood tests, and an electrocardiogram (a test that shows the activity of the heart).

Treatment of Impaction

Impactions are usually treated by moistening and softening the stool with an enema. Enemas must be given very carefully as prescribed by the doctor since too many enemas can damage the bowel. Some patients may need to have stool manually removed from the rectum after it is softened. Glycerin suppositories may also be prescribed. Laxatives that stimulate the bowel and cause cramping must be avoided since they can damage the bowel even more.


BOWEL OBSTRUCTION

Description and Causes

A bowel obstruction may be caused by a narrowing of the intestine from inflammation or damage to the bowel, tumors, scar tissue, hernias, twisting of the bowel, or pressure on the bowel from outside the intestinal tract. It can also be caused by factors that interfere with the function of muscles, nerves, and blood flow to the bowel. Most bowel obstructions occur in the small intestine and are usually caused by scar tissue or hernias. The rest occur in the colon (large intestine) and are usually caused by tumors, twisting of the bowel, or diverticulitis. Symptoms will vary depending on whether the small or large intestine is involved.

The most common cancers that cause bowel obstructions are cancers of the colon, stomach, and ovary. Other cancers, such as lung and breast cancers and melanoma, can spread to the abdomen and cause bowel obstruction. Patients who have had abdominal surgery or radiation are at a higher risk of developing a bowel obstruction. Bowel obstructions are most common during the advanced stages of cancer.

Assessment of Bowel Obstruction

The doctor will do a physical examination to find out whether the patient has abdominal pain, vomiting, or any movement of gas or stool in the bowel. Blood and urine tests may be done to detect any fluid and blood chemistry imbalance or infection. Abdominal x-rays and a barium enema may also be done to find the location of the bowel obstruction.

Treatment of Acute Bowel Obstruction

Patients who have abdominal symptoms that continue to become worse must be monitored frequently to prevent or detect early signs and symptoms of shock and constricting obstruction of the bowel. Medical treatment is necessary to prevent fluid and blood chemistry imbalances and shock.

A nasogastric tube may be inserted through the nose and esophagus into the stomach or a colorectal tube may be inserted through the rectum into the colon to relieve pressure from a partial bowel obstruction. The nasogastric tube or colorectal tube may decrease swelling, remove fluid and gas build-up, or decrease the need for multiple surgical procedures; however, surgery may be necessary if the obstruction completely obstructs the bowel.

Treatment of Chronic, Malignant Bowel Obstruction

Patients who have advanced cancer may have chronic, worsening bowel obstruction that cannot be removed with surgery. Sometimes, the doctor may be able to insert an expandable metal tube called a stent into the bowel to open the area that is blocked.

When neither surgery nor a stent is possible, the doctor may insert a gastrostomy tube through the wall of the abdomen directly into the stomach by a very simple procedure. The gastrostomy tube can relieve fluid and air build-up in the stomach and allow medications and liquids to be given directly into the stomach by pouring them down the tube. A drainage bag with a valve may also be attached to the gastrostomy tube. When the valve is open, the patient may be able to eat or drink by mouth without any discomfort because the food drains directly into the bag. This gives the patient the experience of tasting the food and keeping the mouth moist. Solid food should be avoided because it may block the tubing to the drainage bag.

If the patient's comfort is not improved with a stent or gastrostomy tube, and the patient cannot take anything by mouth, the doctor may prescribe injections or infusions of medications for pain and/or nausea and vomiting.


TO LEARN MORE

Call

For more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 9:00 a.m. to 4:30 p.m. Deaf and hard-of-hearing callers with TTY equipment may call 1-800-332-8615. The call is free and a trained Cancer Information Specialist is available to answer your questions.

Web sites and Organizations

The NCI's Cancer.gov Web site (Http: //cancer.gov) provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support and resources for cancer patients and their families. There are also many other places where people can get materials and information about cancer treatment and services. Local hospitals may have information on local and regional agencies that offer information about finances, getting to and from treatment, receiving care at home, and dealing with problems associated with cancer treatment.

Publications

The NCI has booklets and other materials for patients, health professionals, and the public. These publications discuss types of cancer, methods of cancer treatment, coping with cancer, and clinical trials. Some publications provide information on tests for cancer, cancer causes and prevention, cancer statistics, and NCI research activities. NCI materials on these and other topics may be ordered online or printed directly from the NCI Publications Locator (Http: //cissecure.nci.nih.gov/ncipubs). These materials can also be ordered by telephone from the Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237), TTY at 1-800-332-8615.

LiveHelp

The NCI's LiveHelp service, a program available on several of the Institute's Web sites, provides Internet users with the ability to chat online with an Information Specialist. The service is available from 9:00 a.m. to 7:30 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer.

Write

For more information from the NCI, please write to this address:

National Cancer Institute
Office of Communications
31 Center Drive, MSC 2580
Bethesda, MD 20892-2580


ABOUT PDQ

PDQ is a comprehensive cancer database available on Cancer.gov.

PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at Cancer.gov (Http: //cancer.gov), the NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health, the federal government's focal point for biomedical research.

PDQ contains cancer information summaries.

The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries are available in two versions. The health professional versions provide detailed information written in technical language. The patient versions are written in easy-to-understand, non-technical language. Both versions provide current and accurate cancer information.

The PDQ cancer information summaries are developed by cancer experts and reviewed regularly.

Editorial Boards made up of experts in oncology and related specialties are responsible for writing and maintaining the cancer information summaries. The summaries are reviewed regularly and changes are made as new information becomes available. The date on each summary ("Date Last Modified") indicates the time of the most recent change.

PDQ also contains information on clinical trials.

Some patients have symptoms caused by cancer treatment or by the cancer itself. Patients who have symptoms related to cancer treatment may want to take part in a clinical trial. A clinical trial is a study to answer a scientific question, such as whether one method of treating symptoms is better than another. Trials are based on past studies and what has been learned in the laboratory. Each trial answers certain scientific questions in order to find new and better ways to help cancer patients. During supportive care clinical trials, information is collected about new treatment methods, the risks involved, and how well they do or do not work. If a clinical trial shows that a new treatment is better than one currently being used, the new treatment may become "standard."

Listings of clinical trials are included in PDQ and are available online at Cancer.gov (Http: //cancer.gov/clinical_trials). Descriptions of the trials are available in health professional and patient versions. Many cancer doctors who take part in clinical trials are also listed in PDQ. For more information, call the Cancer Information Service 1-800-4-CANCER (1-800-422-6237); TTY at 1-800-332-8615.

Date Last Modified: 06/2002


If you want to know more about cancer and how it is treated, or if you if you wish to know about clinical trials for your type of cancer, you can call the NCI's Cancer Information Service at 1-800-422-6237, toll free. A trained information specialist can talk with you and answer your questions.


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